-Scaffolds are used to create a suitable 3D spatial environment for cell growth and assembly of different cells (So, looks like we put various cell seeds in the scaffold? why thu?)
-Scaffolds degrade over time, but cuz cells will deposit their ExtraCellular Matrix (ECM) molecules, it retains its architecture for the tissue.
-Traditional methods of making scaffold don't give the exact designed structure, due to fabrication limitation.
-Scaffold should degrade, not from inside(bulk), but from its surface.
-Looks like hydrogels are a good candidate for scaffold, cuz it is easy to make molecule gradient within them to control the growth of cell. But I dont knw how exactly they make this gradient. But I know that microchannles are used.
-Bioreactor is another term used for a device which makes tissue out of a cell culture.
-Cell shape affect diffrentiation through activating RhoA pathway
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